MultipleMyeloma相关论文
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多发性骨髓瘤（MM）是一种克隆浆细胞异常增殖的恶性疾病，在很多国家是血液系统第2位常见恶性肿瘤，多发于老年，目前仍无法治愈。随着新药......
目的:探讨真实世界中泊马度胺治疗复发难治多发性骨髓瘤（MM）的早期效果和安全性。方法:回顾性分析甘肃省人民医院2021年1月至7月收治......
目的:探讨抗B细胞成熟抗原（BCMA）嵌合抗原受体T细胞（CAR-T）再次治疗复发难治多发性骨髓瘤（RRMM）的疗效和安全性。方法:回顾性分析2017年1......
目的:探讨异基因造血干细胞移植（allo-HSCT）治疗高危多发性骨髓瘤（MM）的效果和预后影响因素。方法:回顾性分析2003年4月至2017年3月海......
目的:探讨以伊沙佐米为基础的方案治疗多发性骨髓瘤的效果及安全性。方法:对2020年12月至2021年12月在济宁医学院附属医院接受以伊......
肠道是营养成分消化吸收的主要场所，肠道菌群参与了机体的能量存储、代谢、免疫等活动，在维持机体健康及诱导肿瘤发生等方面具有重要......
目的:评估65岁以上老年多发性骨髓瘤（MM）患者接受自体造血干细胞移植的疗效和安全性。方法:回顾性分析自2006年6月1日至2020年7月31......
Multiple myeloma (MM) is an incurable disease characterized by malignant plasma cell clonal expansion in the bone marrow......
Multiple myeloma (MM) is the second most common hematologic malignancy,and is characterized by the clonal expansion of m......
Major advances in the treatment of multiple myeloma in American Society of Hematology annual meeting
Treatment of multiple myeloma (MM) has advanced dramatically in the past two decades. However, under the conditions of t......
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Methylseleninic acid(MSA)potentiates Bortezomib induced-ER stress and sensitizes apoptosis in multip
Previous studies showed that MSA could induce ER stress which is severe enough to cause apoptosis,and we have shown that......
Comparative analysis of the result of Surgical treatment for myeloma bone disease in the spine and i
Purpose The relative literatures of comparative analysis of the result of surgical treatment for myeloma bone disease(MB......
Purpose :The article gives a case report of interventional therapy in multiple myeloma.Methods: We report a case of a pa......
Epstein-Barr virus infection is associated with clinical characteristics and poor prognosis of multi
Objective Multiple myeloma(MM)is the second most common hematological malignancy characterized by monoclonal proliferati......
Objective Deletion of the short arm of chromosome 17(del17p)is an independent prognostic marker associated with poor cli......
Objective Multiple myeloma(MM)is a hematological malignancy.Although recent progress has been made in understanding the ......
目的 Multiple myeloma(MM)is a hematopoietic malignancy characterized by theclonal proliferation of antibody-secreting pl......
PHLPP sensitizes multiple myeloma cells to bortezomib by increasing LAMP2 Running title:PHLPP in BTZ
Objective Owing to the use of proteasome inhibitor such as bortezomib(BTZ),clinical outcomes of patients with multiple m......
MULTIPLE HIGH-RISK CYTOGENETIC ABERRATIONS CONFER A PROGRESSIVELY NEGATIVE IMPACT ON SURVIVALS OF NE
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The impact of response kinetics following initial therapy for multiple myeloma in the era of novel a
Objective Rapid remission has long been recognized as an important predictor for longtime survival in acute leukemia(AL)......
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Spinal disease in myeloma:cohort analysis at a specialist spinal surgery centre indicates benefit of
Objective: Multiple myeloma osteolytic disease affecting the spine results in vertebral compression fractures.These are ......
DCZ0814 induces apoptosis and G0/G1 phase cell cycle arrest in myeloma by dual inhibition of mTORC1/
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DCZ0801,a novel compound,induces cell apoptosis and cell cycle arrest via MAPK pathway in multiple m
Objective Multiple myeloma(MM) is a refractory malignant hematological malignancy,it is the second most common hematolog......
Monitoring the cytogenetic architecture of minimal residual plasma cells indicates the therapy-induc
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CCL2 promotes macrophage-associated chemoresistance via MCPIP1 dual catalytic activities in multiple
Objective Multiple myeloma(MM)is an incurable hematologic malignancy characterized by the accumulation of monoclonal pla......
Formononetin suppresses hypoxia inducible factor-1α/inflammatory cytokines expression via inhibiting
Object:In multiple myeloma (MM), the hypoxic environment is an important factor causing tumor inflammation, which is str......
Objective Multiple myeloma(MM)is a genetically complex and heterogeneous disease with multiple genomic events associated......
Impact of t(11;14)on the outcome of autologous transplantation in Multiple Myeloma:A multiple center
Objective In the cytogenetic risk-stratification of myeloma,identification of t(11;14)on plasma cells has long been rega......
The potential diagnostic power of CD138+Microparticles from the plasma analysis for multiple myeloma
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The effect of exosome derived from multiple myeloma cell on the IL-6 secretion and osteoblastic diff
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Objective Multiple myeloma(MM)is characterized by an expansion of a clonal plasma cell population.presence of a serum or......
Induction of Bcl-2 independent apoptosis in human myeloma RPMI8226 cells by shRNA-mediated knockdown
Objective DNMT3B,de novo methyltransferase,is related to abnormal methylation of tumor suppressor genes and its overexpr......
Chemokine self-feeding of myeloma cells for extramedullary metastasis revealed by single cell RNA se
Objective To explore the mechanisms of the initial extramedullary translocation of myeloma cells from bone marrow into p......
Inhibitory effect of epirubicin-loaded lipid microbubbles bound with anti-ABCG2 antibody combined wi
To investigate the inhibitory effect of epirubicin (EPI)-loaded lipid microbubbles (MBs) bound with anti-ABCG2 monoclona......
Membrane translocation of Bruton kinase in multiple myeloma cells is associated with osteoclastogeni
Aims: Using bone biopsy samples, we examined whether osteolytic cytokine profile is changed in situ in bone samples of ......
Carfilzomib and dexamethasone (Kd) vs bortezomib and dexamethasone (Vd) in patients with relapsed mu
Objective: ENDEAVOR (NCT01568866) is comparing Kd with Vd in patients with RMM.The primary endpoint is PFS.Secondary end......
Weekly Carfilzomib With Dexamethasone for Patients With Relapsed or Refractory Multiple Myeloma: Upd
Objective: Carfilzomib (K) is a selective proteasome inhibitor that is approved in the United States for the treatment o......
Objective: The article gives a case report of interventional therapy in multiple myeloma.Methods: We report a case of a ......
Carfilzomib,a structural analogue derived from natural product epoxomicin that wasapproved by US FDA for the treatment o......
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Potential relationship and clinical significance of miRNAs and Th17 cytokines in patients with multi
Purposes We evaluated the potential relationship between miRNAs and Th17 cytokines in multiple myeloma (MM) patients.Met......
Upregulation of lncRNA MEG3 promotes osteogenic differentiation of mesenchymal stem cells from multi
Multiple myeloma (MM) is characterized by the impaired osteogenic differentiation of mesenchymal stromal cells (MSCs).Ho......
